Clinical stage of breast cancer by parity, age at birth, and time since birth:: a progressive effect of pregnancy hormones?
Clinical stage of breast cancer by parity, age at birth, and time since birth:: a progressive effect of pregnancy hormones?
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DOI：
10.1158/1055-9965.epi-05-0634
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发表时间：
2006-01-01
影响因子：
3.8
通讯作者：
Kvåle, G
中科院分区：
文献类型：
--
作者：
Albrektsen, G;Heuch, I;Kvåle, G
在怀孕期间或出生后1至2年诊断出的乳腺癌通常发生在晚期。在分娩后不久的高危期，对肿瘤的特征知之甚少。我们在这里探讨疾病的阶段是否根据出生的时间不同。结果基于22,351例挪威乳腺癌患者，胎次为0至5，年龄为20至74岁。在35岁的已产妇女中，II期至IV期肿瘤的比例明显高于未产妇女，以及早二胎妇女(
Breast cancer diagnosed during pregnancy or 1 to 2 years after birth often occurs at a late stage. Little is known about tumor characteristics in the high-risk period shortly after a childbirth. We here explore whether stage of disease differs according to timing of births. Results are based on 22,351 Norwegian breast cancer patients of parity 0 to 5, ages 20 to 74 years. The proportion of stage II to IV tumors was considerably higher among parous than nulliparous women at age = 35 years), as well as women with an early second birth (