How simple is the organization of the olfactory glomerulus? the heterogeneity of so-called periglomerular cells

How simple is the organization of the olfactory glomerulus? the heterogeneity of so-called periglomerular cells
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DOI:
10.1016/s0168-0102(98)00002-9
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发表时间:
1998-02-01
影响因子:
2.9
通讯作者:
Kosaka, T
Kosaka, T
中科院分区:
医学4区
文献类型:
--
作者:
Kosaka, K;Toida, K;Kosaka, T

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近年来,嗅觉系统的研究,特别是分子生物学研究的进展,使其成为了解信息加工神经机制的有用的感觉模型系统之一。在嗅球这一嗅觉系统的主要中枢,小球被认为是传递气味信号和处理嗅觉信息的重要功能单位,但一直被认为只由少数神经元类型组成,因此其神经元和突触组织简单。然而,积累的形态数据显示,每种类型的神经元还可能由几个不同的亚群组成,这表明肾小球的组织可能并不像人们认为的那么简单。在这里,我们描述了肾小球结构组织的一个方面,重点是哺乳动物主嗅球中球周神经元的异质性。(C)1998爱思唯尔爱尔兰科学有限公司。保留所有权利。
Recent progress in the studies of the olfactory system, especially in the molecular biological studies, makes it one of the useful sensory model systems for understanding neural mechanisms for the information processing. In the olfactory bulb, the primary center of the olfactory system, glomeruli are regarded as important functional units in the transmission of odorant signals and in processing the olfactory information, but have been believed to be composed by only a small number of neuronal types and thus to be simple in their neuronal and synaptic organization. However, accumulating morphological data reveal that each type of neurons might further consist of several different subpopulations, indicating that the organization of glomeruli might not be so simple as it was believed. Here we describe an aspect of the structural organization of glomeruli, focusing on the heterogeneities of periglomerular neurons in mammalian main olfactory bulb. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.