Factors associated with colorectal cancer risk perception: the role of polyps and family history
Factors associated with colorectal cancer risk perception: the role of polyps and family history
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DOI：
10.1093/her/cyl049
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发表时间：
2006-10-01
影响因子：
2.4
通讯作者：
Stoddard, Anne M.
中科院分区：
文献类型：
--
作者：
Stark, Jennifer Rider;Bertone-Johnson, Elizabeth R.;Stoddard, Anne M.
目前尚不清楚客观风险因素如何影响与结直肠癌（CRC）风险认知相关的因素。本研究的目的是调查与CRC感知风险相关的因素，并探讨这些关系如何被息肉个人史或CRC家族史所改变。这项研究涉及1646名年龄在50 - 75岁之间的男性和女性完成的邮寄问卷，评估了感知风险，人口统计学和健康史变量以及CRC担忧。参与者是马萨诸塞州中部一个社区医疗小组的初级保健提供者的患者。研究样本似乎对CRC风险有一个普遍准确的认识，在已知风险因素存在的情况下，这种认识会适当增加。在控制所有测量协变量的多变量分析中，财务状况修改了感知风险与息肉个人史之间的关联，而年龄和保险状况修改了感知风险与CRC家族史之间的关联。CRC担忧，自我报告的健康状况，其他癌症的个人病史和对筛查指南的依从性仍然是感知风险的重要预测因素。客观危险因素和社会经济特征之间的潜在相互作用应在纵向研究中进一步探讨。
It is unclear how objective risk factors influence the factors associated with colorectal cancer (CRC) risk perception. The goals of this study were to investigate factors associated with perceived risk of CRC and to explore how these relationships were modified by personal history of polyps or family history of CRC. The study involved a mailed questionnaire completed by 1646 men and women aged 50-75 years, which assessed perceived risk, demographic and health history variables and CRC worry. Participants were patients of primary care providers in a community medical group in central Massachusetts. The study sample seemed to have a generally accurate perception of CRC risk, which was appropriately increased in the presence of known risk factors. In multivariable analyses that controlled for all measured covariates, financial situation modified the association between perceived risk and a personal history of polyps, while age and insurance status modified the association between perceived risk and family history of CRC. CRC worry, self-reported health, personal history of other cancer and compliance with screening guidelines remained significant predictors of perceived risk. Potential interactions between objective risk factors and socioeconomic characteristics should be further explored in longitudinal studies.