The impact of school opening model on SARS-CoV-2 community incidence and mortality
The impact of school opening model on SARS-CoV-2 community incidence and mortality
复制标题
DOI：
10.1038/s41591-021-01563-8
复制
发表时间：
2021-10-27
期刊：
影响因子：
82.9
通讯作者：
Nelson, Richard
中科院分区：
文献类型：
--
作者：
Ertem, Zeynep;Schechter-Perkins, Elissa;Nelson, Richard
美国一项全国性队列研究的结果表明，学校可以重新开放，进行面对面学习，而不会大幅增加社区SARS-CoV-2的病例率。相对于完全远程教育，传统和混合面对面教育模式对SARS-CoV-2感染社区发病率的作用尚不清楚。我们使用回顾性全国队列进行了一项事件研究，评估学校开学后12周内（2020年7月至9月，Delta变异占主导地位之前）学校模式对SARS-CoV-2病例的影响，按美国人口普查地区分层。在控制了开学前的病例率趋势、州一级的缓解措施和社区活动水平后，在美国大部分地区，面对面学习的县与远程学校模式的县的SARS-CoV-2发病率没有统计学差异。在南方，与偏远地区相比，以混合或传统模式开放的县每周病例数显著持续增加，每周影响范围从9.8（95%置信区间（CI）= 2.7-16.1）至21.3（95% CI = 9.9-32.7）每10万人中的病例增加，这是由0-9奥尔兹和成人的病例增加所驱动的。学校可以重新开放进行面对面学习，而不会大幅增加社区SARS-CoV-2的发病率;然而，影响是可变的。需要进行更多的研究，以更充分地阐明所观察到的区域差异的根本原因。
Results from a nationwide cohort study in the United States indicates that schools can reopen for in-person learning without substantially increasing community case rates of SARS-CoV-2.The role that traditional and hybrid in-person schooling modes contribute to the community incidence of SARS-CoV-2 infections relative to fully remote schooling is unknown. We conducted an event study using a retrospective nationwide cohort evaluating the effect of school mode on SARS-CoV-2 cases during the 12 weeks after school opening (July-September 2020, before the Delta variant was predominant), stratified by US Census region. After controlling for case rate trends before school start, state-level mitigation measures and community activity level, SARS-CoV-2 incidence rates were not statistically different in counties with in-person learning versus remote school modes in most regions of the United States. In the South, there was a significant and sustained increase in cases per week among counties that opened in a hybrid or traditional mode versus remote, with weekly effects ranging from 9.8 (95% confidence interval (CI) = 2.7-16.1) to 21.3 (95% CI = 9.9-32.7) additional cases per 100,000 persons, driven by increasing cases among 0-9 year olds and adults. Schools can reopen for in-person learning without substantially increasing community case rates of SARS-CoV-2; however, the impacts are variable. Additional studies are needed to elucidate the underlying reasons for the observed regional differences more fully.