Genome-wide analysis of Sox genes in Drosophila melanogaster
Genome-wide analysis of Sox genes in Drosophila melanogaster
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DOI：
10.1016/s0925-4773(01)00529-9
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发表时间：
2001-12-01
影响因子：
2.6
通讯作者：
Girard, F
中科院分区：
文献类型：
--
作者：
Crémazy, F;Berta, P;Girard, F
Sox家族的基因编码进化上保守的含有转录因子的HMG盒，这些转录因子在发育过程中细胞决定/分化的各种事件中发挥关键作用。通过经典的分子克隆方法和对果蝇全基因组的彻底筛选，估计果蝇中Sox基因的总数为8个。在这里，我们报告的胚胎和幼虫的表达模式的四个以前未知的Sox基因，通过抗体染色和原位杂交实验。(C)2001爱思唯尔科学爱尔兰有限公司保留所有权利。
Genes of (he Sox family encode evolutionarily conserved HMG box containing transcription factors, which play key roles in various events of cell determination/differentiation during development. The total number of Sox genes in Drosophila melanogaster was estimated to be eight, after classical molecular cloning approaches and exhaustive screening of the complete Drosophila genome. Here we report the embryonic and larval expression pattern of four previously uncharacterized Sox genes, through antibody staining and in situ hybridization experiments. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.