Antigenic phenotype of pigment cell lesions: a study of melanoma, its precursor lesions and heterogeneity in metastatic melanoma.
Antigenic phenotype of pigment cell lesions: a study of melanoma, its precursor lesions and heterogeneity in metastatic melanoma.
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色素细胞病变的抗原表型：黑色素瘤、其前体病变和转移性黑色素瘤异质性的研究。
DOI：
10.1111/1523-1747.ep12265530
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发表时间：
1985
期刊：
影响因子：
--
通讯作者：
Kirkwood,JM
中科院分区：
文献类型：
--
作者：
Ernstoff,MS;Duray,P;Stenn,K;Kirkwood,JM
Expression of surface antigens on cells comprising malignant, dysplastic, and benign pigment cell lesions has been evaluated in situ using an avidin-biotin immunohistologic technique. We have demonstrated expression of HLA-DR, β2-microglobulin, and 2 melanoma-associated antigens (MAA) in a range of benign and malignant lesion, and have confirmed the close association of HLA-DR and MAA on malignant lesions. In addition, 5 subcutaneous lesions removed at the same time from one individual were evaluated. Clinical and histologic appearance differed among lesions although the antigenic patterns were similar.
