Reticulate acropigmentation of Kitamura
Reticulate acropigmentation of Kitamura
复制标题
北村网状肢端色素沉着
DOI：
10.32388/zz1lv5
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发表时间：
2020
期刊：
影响因子：
--
通讯作者：
K. Qayed
中科院分区：
文献类型：
--
作者：
Gilles G. Lestringant;G. A. Aal;P. M. Frossard;K. Qayed
一种罕见的遗传性、色素沉着的皮肤病，特征是从童年到成年--发病时出现网状、轻微抑郁、界限清晰的棕色黄斑皮损，没有色素减退，影响手脚背部，偶尔会进展到四肢、颈部、前额和/或躯干。此外，还可观察到皮肤纹路中断和掌底凹陷。组织学上，色素沉着的病变表现为网脊稍长变薄，轻度角化过度而无角化不良，无色素性失禁。
A rare, genetic, hyperpigmentation of the skin disease characterized by childhood to adulthood-onset of reticulate, slightly depressed, sharply demarcated, brown, macular skin lesions without hypopigmentation, affecting the dorsa of the hands and feet, and, occasionally, progressing to involve limbs, neck, forehead and/or trunk. Interrupted dermatoglyphics and palmoplantar pits may be additionally observed. Histologically, hyperpigmented lesions show slightly elongated and thinned rete ridges, mild hyperkeratosis without parakeratosis and absence of incontinentia pigmenti.