Cytotoxic triterpene saponins from Alternanthera philoxeroides

Cytotoxic triterpene saponins from Alternanthera philoxeroides
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DOI:
10.1080/10286020802684656
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发表时间:
2009-01-01
影响因子:
1.7
通讯作者:
Duan, Hong-Quan
Duan, Hong-Quan
中科院分区:
医学4区
文献类型:
--
作者:
Fang, Jin-Bo;Yao, Zhi;Duan, Hong-Quan

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从空心莲子草(Alternanthera philoxeroides)地上部分分得4个新的五环三萜皂苷,分别命名为空心莲子草皂苷A-D(1-4)。通过1D-和2D-NMR实验和MS分析确定了它们的结构。Philoxeroidesides A-D(1-4)对SK-N-SH和HL-60细胞株具有细胞毒活性。
Four new pentacyclic triterpene saponins, philoxeroidesides A-D (1-4) were isolated from the aerial parts of Alternanthera philoxeroides. Their structures were elucidated on the basis of 1D- and 2D-NMR experiments and MS analyses. Philoxeroidesides A-D (1-4) showed cytotoxic activities against SK-N-SH and HL60 cell lines.