Detection of Measles Virus RNA in Air and Surface Specimens in a Hospital Setting
Detection of Measles Virus RNA in Air and Surface Specimens in a Hospital Setting
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DOI：
10.1093/infdis/jiv465
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发表时间：
2016-02-15
影响因子：
6.4
通讯作者：
Stehle, John R., Jr.
中科院分区：
文献类型：
--
作者：
Bischoff, Werner E.;McNall, Rebecca J.;Stehle, John R., Jr.
麻疹病毒（MeV）已知具有高度传染性，传染期从出疹前 4 天持续到出疹后 4 天。一名未接种疫苗的年轻女性患者经直接流行病学联系证实患有麻疹，于皮疹发作后第 5 天住院。环境样本是在住院的 4 天期间在单人病房内收集的。皮疹出现后第 5-8 天，空气样本、表面样本和呼吸器中可检测到 MeV RNA。这是第一份 MeV 环境监测报告，结果表明医疗机构中可能存在感染 MeV 的污染物。
Measles virus (MeV) is known to be highly contagious, with an infectious period lasting from 4 days before to 4 days after rash onset. An unvaccinated, young, female patient with measles confirmed by direct epidemiologic link was hospitalized on day 5 after rash onset. Environmental samples were collected over the 4-day period of hospitalization in a single room. MeV RNA was detectable in air specimens, on surface specimens, and on respirators on days 5-8 after rash onset. This is the first report of environmental surveillance for MeV, and the results suggest that MeV-infected fomites may be present in healthcare settings.