Sleep Disturbances as a Risk Factor for Stroke.
Sleep Disturbances as a Risk Factor for Stroke.
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DOI：
10.5853/jos.2017.02887
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发表时间：
2018-01
影响因子：
8.2
通讯作者：
Yun CH
中科院分区：
文献类型：
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作者：
Koo DL;Nam H;Thomas RJ;Yun CH
睡眠是一个由大脑精心安排的生命过程，包括快速眼动（REM）和非快速眼动（NREM）睡眠之间的周期性转换。NREM睡眠期间的自主宁静的特征在于迷走神经支配和稳定的呼吸，为心血管-神经轴提供了恢复稳态的机会，以响应清醒期间造成的使用、痛苦或疲劳。在REM睡眠期间，交感迷走神经平衡的突然不规则摆动作为静息心血管系统的阶段性负荷。任何导致睡眠缩短或不完整的原因，如睡眠限制、睡眠呼吸暂停、失眠、睡眠期间的周期性肢体运动和轮班工作，不仅会损害心血管恢复，还会对心血管系统造成压力。据报道，睡眠障碍在中风和其他心血管疾病的发生中发挥着作用。本文旨在提供有关睡眠异常在卒中发生发展中作用的最新信息，讨论最近研究结果的意义，并帮助卒中临床医生和研究人员了解识别和管理睡眠病理对卒中预防和护理的重要性。
Sleep, a vital process of human being, is carefully orchestrated by the brain and consists of cyclic transitions between rapid eye movement (REM) and non-REM (NREM) sleep. Autonomic tranquility during NREM sleep is characterized by vagal dominance and stable breathing, providing an opportunity for the cardiovascular-neural axis to restore homeostasis, in response to use, distress or fatigue inflicted during wakefulness. Abrupt irregular swings in sympathovagal balance during REM sleep act as phasic loads on the resting cardiovascular system. Any causes of sleep curtailment or fragmentation such as sleep restriction, sleep apnea, insomnia, periodic limb movements during sleep, and shift work, not only impair cardiovascular restoration but also impose a stress on the cardiovascular system. Sleep disturbances have been reported to play a role in the development of stroke and other cardiovascular disorders. This review aims to provide updated information on the role of abnormal sleep in the development of stroke, to discuss the implications of recent research findings, and to help both stroke clinicians and researchers understand the importance of identification and management of sleep pathology for stroke prevention and care.
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影响因子：
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