Mutagenic and carcinogenic hazards of settled house dust I: Polycyclic aromatic hydrocarbon content and excess lifetime cancer risk from preschool exposure
Mutagenic and carcinogenic hazards of settled house dust I: Polycyclic aromatic hydrocarbon content and excess lifetime cancer risk from preschool exposure
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DOI：
10.1021/es702449c
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发表时间：
2008-03-01
影响因子：
11.4
通讯作者：
White, Paul A.
中科院分区：
文献类型：
--
作者：
Maertens, Rebecca M.;Yang, Xiaofeng;White, Paul A.
沉降的房屋灰尘（SHD）可能是儿童室内暴露于包括多环芳烃（PAH）在内的有害物质的重要来源。在这项研究中，从51个家庭筛选真空吸尘器灰尘的有机提取物进行了检查，通过GC/MS的存在下的13个多环芳烃。多环芳烃被发现在所有样本的总多环芳烃的水平范围在1.5和325微克（-1）。在SHD的PAH浓度与相应的家庭问卷中所包含的信息相关。分析表明，多环芳烃的水平是负相关的非燃烧活动，如真空清洁频率。进行了风险评估，以评估在SHD中摄入多环芳烃的学龄前儿童所面临的终身癌症风险。评估显示，90%的家庭（
Settled house dust (SHD) may be a significant source of children's indoor exposure to hazardous substances including polycyclic aromatic hydrocarbons (PAHs). In this study, organic extracts of sieved vacuum cleaner dust from 51 homes were examined for the presence of 13 PAHs via GC/MS. PAHs were found in all samples with levels of total PAHs ranging between 1.5 and 325 mu g g(-1). The PAH concentrations in the SHD were correlated with information contained in corresponding household questionnaires. Analyses showed levels of PAHs to be negatively associated with noncombustion activities such as vacuum cleaning frequency. A risk assessment was conducted to evaluate the excess lifetime cancer risks posed to preschool aged children who ingested PAHs in SHD. The assessment revealed that exposure to PAHs at levels found in 90% of the homes (