Brain mapping of deception and truth telling about an ecologically valid situation: Functional MR imaging and polygraph investigation - Initial experience
Brain mapping of deception and truth telling about an ecologically valid situation: Functional MR imaging and polygraph investigation - Initial experience
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DOI：
10.1148/radiol.2382050237
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发表时间：
2006-02-01
期刊：
影响因子：
19.7
通讯作者：
Williams, JM
中科院分区：
文献类型：
--
作者：
Mohamed, FB;Faro, SH;Williams, JM
目的：检查神经相关的欺骗和讲真话，通过使用功能性磁共振（MR）成像技术和生态有效的任务，并与那些标准的测谎examination.Materials和方法的结果进行比较：所有受试者给予书面知情同意，这是由该机构审查委员会批准的研究，这是由德雷克塞尔大学。11名健康受试者（5名女性和6名男性受试者;平均年龄，28.9岁）被随机分配到有罪受试者组或无罪受试者组。每组包括两个单独的功能磁共振成像条件：“只说谎条件”和“只说真话条件”。“只有谎言的条件被用来比较大脑活动在一个已知的谎言控制问题和一个主观的谎言相关的问题。只说真话的条件被用来比较在已知的真实反应控制问题和主观的真实反应相关的问题的大脑活动。采用回波平面序列采集功能性MR图像，并进行统计学分析。生理反应进行了测量与一个标准的四通道测谎仪instrument.Results：在欺骗的过程中，特定区域的额叶（左内侧和左下额叶），颞叶（右海马和右颞中回），枕叶（左舌回），前扣带回，右梭状回，右叶下回显着活跃。在说真话的过程中，额叶（左胼胝体下回或豆状核）和颞叶（左颞下回）的特定区域明显活跃。测谎仪检查显示，92%的准确性在欺骗性科目和70%的准确性在truthingsubject.Conclusion：特定区域的大脑参与欺骗或讲真话可以描绘与功能磁共振成像。(c)RSNA，2006年。
Purpose: To examine the neural correlates during deception and truth telling by using a functional magnetic resonance (MR) imaging technique and an ecologically valid task and to compare the results with those of a standard polygraph examination.Materials and Methods: All subjects gave written informed consent for this HIPAA-approved study, which was approved by the institutional review board of Drexel University. Eleven healthy subjects (five female and six male subjects; mean age, 28.9 years) were randomly assigned to the group of guilty subjects or the group of nonguilty subjects. Each group consisted of two separate functional MR imaging conditions: "lie-only condition" and "truth-only condition." The lie-only condition was used to compare brain activity during a known lie to control questions and a subjective lie to relevant questions. The truth-only condition was used to compare brain activity during a known truthful response to control questions and a subjective truthful response to relevant questions. Functional MR images were acquired with an echoplanar sequence, and statistical analysis was performed. Physiologic responses were measured with a standard four-channel polygraph instrument.Results: During the deception process, specific areas of the frontal lobe (left medial and left inferior frontal lobes), temporal lobe (right hippocampus and right middle temporal gyrus), occipital lobe (left lingual gyros), anterior cingulate, right fusiform gyros, and right sublobar insula were significantly active. During the truth telling process, specific areas of the frontal (left subcallosal gyros or lentiform nucleus) and temporal (left inferior temporal gyros) lobes were significantly active. The polygraph examination revealed 92% accuracy in deceptive subjects and 70% accuracy in truthful subjects.Conclusion: Specific areas of the brain involved in deception or truth telling can be depicted with functional MR imaging. (c) RSNA, 2006.