Transcriptional response of Escherichia coli to TPEN

Transcriptional response of Escherichia coli to TPEN
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DOI:
10.1128/jb.00680-06
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发表时间:
2006-09-01
影响因子:
3.2
通讯作者:
Crowder, Michael W.
Crowder, Michael W.
中科院分区:
生物学3区
文献类型:
--
作者:
Sigdel, Tara K.;Easton, J. Allen;Crowder, Michael W.

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利用DNA微阵列检测大肠杆菌对N,N,N ',N'-四(2-吡啶基甲基)乙二胺(TPEN)的转录反应。55个转录物显著上调,包括所有受Zur调控的基因和许多受Fur调控的基因。在相同的TPEN处理的细胞中,46个转录物显著下调。
DNA microarrays were used to probe the transcriptional response of Escherichia coli to N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine (TPEN). Fifty-five transcripts were significantly up-regulated, including all of the genes that are regulated by Zur and many that are regulated by Fur. In the same TPEN-treated cells, 46 transcripts were significantly down-regulated.