Effect of intensive lipid lowering with atorvastatin on renal function in patients with coronary heart disease: The treating to new targets (TNT) study
Effect of intensive lipid lowering with atorvastatin on renal function in patients with coronary heart disease: The treating to new targets (TNT) study
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DOI：
10.2215/cjn.04371206
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发表时间：
2007-11-01
影响因子：
9.8
通讯作者：
Wenger, Nanette K.
中科院分区：
文献类型：
--
作者：
Shepherd, James;Kastelein, John J. P.;Wenger, Nanette K.
背景和目标：数据表明阿托伐他汀可能具有肾保护作用。这项治疗新目标研究的子分析调查了与 10 毫克阿托伐他汀治疗冠心病患者相比，80 毫克阿托伐他汀强化降脂对肾功能的影响。 设计、设置、参与者和测量：总共 10,001 名冠心病患者，LDL 胆固醇水平为
Background and objectives: Data suggest that atorvastatin may be nephroprotective. This subanalysis of the Treating to New Targets study investigated how intensive lipid lowering with 80 mg of atorvastatin affects renal function when compared with 10 mg in patients with coronary heart disease.Design, setting, participants, & measurements: A total of 10,001 patients with coronary heart disease and LDL cholesterol levels of