Allergenic components of vaccines and avoidance of vaccination-related adverse events.
Allergenic components of vaccines and avoidance of vaccination-related adverse events.
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DOI：
10.1007/s11882-001-0091-6
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发表时间：
2001-01-01
期刊：
影响因子：
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通讯作者：
Fasano, M B
中科院分区：
文献类型：
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作者：
Georgitis, J W;Fasano, M B
疫苗对传染病的流行产生了巨大影响，但是，在某些特定个体中，注射会带来过敏反应的风险。幸运的是，大多数人对疫苗没有过敏反应。对于鸡蛋过敏的个体，在接种特定疫苗之前必须小心；本文提供的算法给出了皮肤测试和脱敏的具体建议。对于接受麻疹、腮腺炎、风疹疫苗的个人来说，不需要这种算法，因为过敏反应的风险极低，即使是那些已知鸡蛋蛋白敏感性的人也是如此。有些人对明胶敏感，可能会引起过敏反应。选定的疫苗含有抗生素药物，因此必须注意个人是否有任何已知的药物敏感性，特别是对新霉素、多粘菌素 B 或两性霉素 B。最后，疫苗防腐剂可能会引起反应，但这种情况很少发生。
Vaccines have had a dramatic effect on the prevalence of communicable diseases, but, in selected individuals, the injection presents a risk of anaphylaxis. Fortunately, most people have no allergic reactions to vaccines. In egg-allergic individuals, care must be taken before administering specific vaccines; the algorithm provided in this article gives specific recommendations for skin testing and desensitization. This algorithm is not needed for individuals receiving the measles-mumps-rubella vaccine because the risk of anaphylaxis is extremely low, even in those with known egg-protein sensitivity. Some individuals have gelatin sensitivity, which may cause anaphylaxis. Selected vaccines contain antibiotic drugs, so it is important to note if an individual has any known drug sensitivity, especially to neomycin, polymyxin B, or amphotericin B. Lastly, vaccine preservatives may cause reactions, but this occurs very infrequently.