Noninvasive evaluation of splanchnic tissue oxygenation using near-infrared spectroscopy in preterm neonates
Noninvasive evaluation of splanchnic tissue oxygenation using near-infrared spectroscopy in preterm neonates
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DOI：
10.3109/14767058.2010.511335
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发表时间：
2011-04-01
影响因子：
1.8
通讯作者：
Sood, Beena G.
中科院分区：
文献类型：
--
作者：
Cortez, Josef;Gupta, Meenakshi;Sood, Beena G.
目的：评估在出生后14天内的早产儿中进行连续局部脑组织氧饱和度（rsSO₂）监测的可行性和安全性。
方法：孕周＜30周的早产儿在出生后48小时内于左侧脐旁区域放置近红外光谱（NIRS）传感器。每30秒记录一次rsSO₂。记录包括脉搏血氧饱和度（SaO₂）在内的临床数据。组织氧摄取分数（FTOE）按如下公式计算：(SaO₂ - rsSO₂)×100 / SaO₂。
结果：在纳入的21名婴儿中，有2名因皮肤破损和数据缺失而被排除。每日平均rsSO₂值在最初9天内下降（p＜0.0001），随后从第10天（D10）到第14天上升（p = 0.0061）。与无喂养不耐受的婴儿相比，有喂养不耐受的婴儿rsSO₂更低且FTOE更高（p = 0.0043）。rsSO₂占FTOE变异的≥99.5%。2名患有坏死性小肠结肠炎（NEC）的新生儿rsSO₂持续偏低，在其之前或之后伴有变异性丧失以及rsSO₂极高的情况。
结论：我们报告了少数早产儿在出生后2周内进行rsSO₂监测的可行性、安全性以及其数值范围。
Objective. aEuro integral To evaluate feasibility and safety of continuous rsSO(2) monitoring in preterm infants in the first 14 days of life.Methods. aEuro integral Preterm neonates < a parts per thousand currency sign30 weeks' gestation had a NIRS sensor placed in the left paraumbilical region within 48 h of birth. rsSO(2) was recorded every 30 s. Clinical data including pulse oximetry (SaO(2)) were recorded. Fractional tissue oxygen extraction (FTOE) was computed as follows: (SaO(2) -- rsSO(2)) xx 100/SaO(2).Results. aEuro integral Of 21 infants enrolled, 2 were excluded because of skin breakdown and missing data. Daily mean rsSO(2) values decreased over the first 9 days (p < 0.0001) followed by an increase from day 10 (D10) to D14 (p == 0.0061). rsSO(2) was lower and FTOE was higher in infants with feeding intolerance compared to those without feeding intolerance (p == 0.0043). rsSO(2) accounted for >= a parts per thousand yen99.5%% of the variance in FTOE. Two neonates with NEC had persistently low rsSO(2) with loss of variability preceded or followed by very high rsSO(2).Conclusions. aEuro integral We have reported feasibility, safety and ranges for rsSO(2) for a small number of preterm infants in the first 2 weeks of life.