Detection and molecular characterisation of rotavirus and norovirus infections in Jordanian children with acute gastroenteritis
Detection and molecular characterisation of rotavirus and norovirus infections in Jordanian children with acute gastroenteritis
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DOI：
10.1007/s00705-011-0996-x
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发表时间：
2011-08-01
影响因子：
2.7
通讯作者：
Cunliffe, Nigel A.
中科院分区：
文献类型：
--
作者：
Kaplan, Nasser M.;Kirby, Andrew;Cunliffe, Nigel A.
轮状病毒和诺如病毒是全球儿科胃肠炎的重要原因，但约旦尚未报告病毒基因型研究。我们对2006年1月至2007年12月间约旦因急性胃肠炎住院的儿童进行了分子流行病学研究。在368名儿童中，轮状病毒和诺如病毒感染的检出率分别为49.5%和11.4%。轮状病毒基因型P[8]，G1（56%），P[4]，G2（14%）和P[8]，G9（13%）最常见，与全球轮状病毒监测研究的结果一致。诺如病毒GII.3是最常检测到的基因型，其次是GII.4，与GII.4占主导地位的大多数研究形成对比。
Rotavirus and norovirus are globally important causes of paediatric gastroenteritis, but no studies of viral genotypes have been reported from Jordan. We undertook a molecular epidemiological study in children hospitalised with acute gastroenteritis in Jordan between January 2006 and December 2007. Among 368 children, rotavirus and norovirus infections were detected in 49.5% and 11.4% of children, respectively. Rotavirus genotypes P[8],G1 (56%), P[4],G2 (14%) and P[8],G9 (13%) were most commonly identified, consistent with results of global rotavirus surveillance studies. Norovirus GII.3 was the most commonly detected genotype, followed by GII.4, contrasting with most studies in which GII.4 has predominated.