Early vitreous surgery for aggressive posterior retinopathy of prematurity
Early vitreous surgery for aggressive posterior retinopathy of prematurity
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DOI：
10.1016/j.ajo.2006.05.048
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发表时间：
2006-10-01
影响因子：
4.2
通讯作者：
Nishina, Sachiko
中科院分区：
文献类型：
--
作者：
Azuma, Noriyuki;Ishikawa, Kaoru;Nishina, Sachiko
目的：评价早期玻璃体切除术治疗侵袭性早产儿后路视网膜病变（ROP）阻止视网膜脱离进展的疗效。设计：回顾性、非比较性、连续的病例系列。方法：22眼（15例）侵袭性后路ROP患者行玻璃体切除术，保留或不保留晶状体，因为视网膜光凝术未能阻止纤维血管增殖的进展，尽管进行了早期，密集和早期再治疗。我们在镜下评估了视网膜附着和中央凹形成的状态以及视觉行为固定的存在与否。结果：随访6 ~ 12个月（平均9个月）。6只眼（100%）进行了保留晶状体的玻璃体切除术，出现了大的牵引性视网膜脱离。相比之下，在玻璃体切除和晶状体切除术中，16只眼（100%）的视网膜完全附着，9只眼（56%）有中央凹结构，14只眼（88%）有稳定固定。结论：早期玻璃体切除术是预防侵袭性后路ROP视网膜脱离的有效方法。
PURPOSE: To assess the efficacy of early vitrectomy for aggressive posterior retinopathy of prematurity (ROP) to stop progression of retinal detachment.DESIGN: Retrospective, noncomparative, consecutive case series.METHODS: Twenty-two eyes (15 patients) with aggressive posterior ROP underwent vitrectomy with or without lens sparing, because retinal photocoagulation failed to stop progression of fibrovascular proliferation, despite being performed early, densely, and with early retreatment. We assessed the status of retinal attachment and foveal formation ophthalmoscopically and the presence or absence of fixation of visual behavior.RESULTS: Follow-up ranged from six to 12 months (mean, 9 months). Six eyes (100%) in which a lens,sparing vitrectomy was performed developed a large tractional retinal detachment. In contrast, the retinas were completely reattached in 16 eyes (100%) in which vitrectomy with lensectomy was performed, nine eyes (56%) had foveal configuration, and 14 eyes (88%) had steady fixation.CONCLUSIONS: These results suggest that early vitrectomy is effective for preventing retinal detachment in aggressive posterior ROP.