Skin cancers at the National University Hospital of Cotonou from 1985 to 2004
Skin cancers at the National University Hospital of Cotonou from 1985 to 2004
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DOI：
10.1111/j.1365-4632.2007.03459.x
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发表时间：
2007-10-01
影响因子：
3.6
通讯作者：
do Ango-Padonou, Florencia
中科院分区：
文献类型：
--
作者：
Adegbidi, Hugues;Yedomon, Hubert;do Ango-Padonou, Florencia
背景皮肤癌是欧洲和美国成人中最常见的癌症。然而，据报道，美国黑人和非洲的发病率较低。本研究探讨了发病率的黑色素瘤和表皮样癌和基底细胞癌在科托努在Benin.Methods超过20年，收集了19例患者的记录，其中16个是一个回顾性流行病学研究的主题。发生率为0.00066%，男女比例为1.28，平均年龄为54.81岁。表皮样癌、黑色素瘤和基底细胞癌的平均诊断年龄分别为61.66岁、59.40岁和54.56岁。表皮样癌的平均病程是黑色素瘤和基底细胞癌的6-10倍。在研究中纳入的16名患者中，有5名是白化病患者。在这一组中，频率为31.25%。讨论皮肤癌在我们的系列中的极端罕见不能仅仅是招募偏倚的结果。它反映了实际情况。我们所有的黑色素瘤病例都发生在足底。这种与其他研究的不一致可能是由于我们的系列的大小。在我们的癌症病例中，疾病的持续时间与以前在塞内加尔达喀尔进行的研究结果相当。在我们的研究中，眼皮肤白化病是主要的preneoplastic factor.Conclusion这项研究证实了皮肤癌的发病率低，在黑色的人口，事实上，基底细胞癌影响一个相对年轻的人口，黑色素瘤的好发性肢端位置在黑色的个人。
Background Skin cancer is the most common form of cancer occurring in adults in Europe and the USA. A low incidence has been reported in the black American population and in Africa, however. This study investigates the incidence of melanoma and epidermoid and basocellular carcinoma at Cotonou in Benin.Methods Over 20 years, 19 patient records were collected, 16 of which were the subject of a retrospective epidemiologic study.Results The main characteristic of skin cancer in the Department of Dermatology, Cotonou, Benin was its extreme rarity. The frequency was 0.00066%, with a male to female ratio of 1.28 and a mean age of 54.81 years. The mean ages at diagnosis for epidermoid carcinoma, melanoma, and basocellular carcinoma were 61.66, 59.40, and 54.56 years, respectively. The mean duration of epidermoid carcinoma was 6-10 times longer than that of melanoma and basocellular carcinoma. Of the 16 patients included in the study, five were albinos. In this group, the frequency was 31.25%.Discussion The extreme rarity of skin cancers in our series cannot be the result of recruitment bias alone. It reflects the actual situation. All of our cases of melanoma were in a plantar location. This inconsistency with other studies is probably a result of the size of our series. The duration of disease in our cases of carcinoma was comparable with the results obtained in a previous study in Dakar, Senegal. In our study, oculocutaneous albinism was the main preneoplastic factor.Conclusion This study confirms the low incidence of skin cancer in the black population, the fact that basocellular carcinoma affects a relatively young population, and the predilection of melanoma for acral locations in black individuals.