Distorted own-body representations in patients with dizziness and during caloric vestibular stimulation
Distorted own-body representations in patients with dizziness and during caloric vestibular stimulation
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头晕患者和热量前庭刺激期间自身身体表征的扭曲
DOI：
10.1007/s00415-018-8906-8
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发表时间：
2018
影响因子：
6
通讯作者：
F. Mast
中科院分区：
文献类型：
--
作者：
C. Lopez;E. Nakul;Nora Preuss;M. Elzière;F. Mast
越来越多的证据表明，前庭障碍引起的缺陷远远超出了不平衡，视觉障碍和空间认知。然而，前庭障碍如何影响自身的身体表征，特别是感知的身体形状和大小，一直被忽视。在这里，我们探索前庭的贡献，自己的身体表征使用两种方法。研究1使用剑桥人格解体量表中的6个项目，测量了60名头晕患者和60名健康对照者的自身表征扭曲的发生率和严重程度。12%的患者经历过扭曲的自身身体表征（他们的手或脚感觉更大或更小），37%的患者报告了异常的主体感，35%的患者报告了对身体的所有权丧失，22%的患者报告了身体的剥离。这些比例在患者中大于对照组。研究2的目的是测试是否前庭器官的人工刺激在健康志愿者中产生可比较的自身身体表征的扭曲。我们比较了右温/左冷前庭刺激（CVS），左温/右冷CVS和假CVS的左，右手使用指向任务的内部模型的影响。手背的感知长度增加，特别是在左暖/右冷CVS，这种效果被发现双手。我们的研究表明前庭对自身身体表征的贡献，应该有助于理解头晕患者的复杂神经病学。
There is increasing evidence that vestibular disorders evoke deficits reaching far beyond imbalance, oscillopsia and spatial cognition. Yet, how vestibular disorders affect own-body representations, in particular the perceived body shape and size, has been overlooked. Here, we explored vestibular contributions to own-body representations using two approaches. Study 1 measured the occurrence and severity of distorted own-body representations in 60 patients with dizziness and 60 healthy controls using six items from the Cambridge Depersonalization Scale. 12% of the patients have experienced distorted own-body representations (their hands or feet felt larger or smaller), 37% reported abnormal sense of agency, 35% reported disownership for the body, and 22% reported disembodiment. These proportions were larger in patients than controls. Study 2 aimed at testing whether artificial stimulation of the vestibular apparatus produced comparable distortions of own-body representations in healthy volunteers. We compared the effects of right-warm/left-cold caloric vestibular stimulation (CVS), left-warm/right-cold CVS and sham CVS on internal models of the left and right hands using a pointing task. The perceived length of the dorsum of the hand was increased specifically during left-warm/right-cold CVS, and this effect was found for both hands. Our studies show a vestibular contribution to own-body representations and should help understand the complex symptomatology of patients with dizziness.