SPECT detectors: the Anger Camera and beyond.
SPECT detectors: the Anger Camera and beyond.
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DOI：
10.1088/0031-9155/56/17/r01
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发表时间：
2011-09-07
影响因子：
3.5
通讯作者：
Furenlid LR
中科院分区：
文献类型：
--
作者：
Peterson TE;Furenlid LR
开发能够提供关于伽马射线相互作用的空间信息的辐射探测器是核医学成像以及最终单光子发射计算机断层扫描的关键技术之一。连续NaI（Tl）闪烁体晶体耦合到光电倍增管阵列，几乎普遍被称为愤怒相机后，其发明者，长期以来一直是占主导地位的SPECT探测器系统。然而，多年来已经研究了许多替代材料和配置。技术进步以及心脏和临床前成像等专业应用的重要性不断涌现，推动了创新，因此Anger Camera的替代品现在已成为商业成像系统的一部分。计算能力的提高使应用先进的信号处理和估计方案以更好地利用探测器信号中所含的信息变得切实可行。在这篇综述中，我们讨论了SPECT探测器的关键性能特性，并调查了闪烁体和半导体探测器及其读数的发展情况，着眼于一些实际问题，至少部分原因是愤怒相机在临床上的持续流行。
The development of radiation detectors capable of delivering spatial information about gamma-ray interactions was one of the key enabling technologies for nuclear medicine imaging and, eventually, single-photon emission computed tomography (SPECT). The continuous NaI(Tl) scintillator crystal coupled to an array of photomultiplier tubes, almost universally referred to as the Anger Camera after its inventor, has long been the dominant SPECT detector system. Nevertheless, many alternative materials and configurations have been investigated over the years. Technological advances as well as the emerging importance of specialized applications, such as cardiac and preclinical imaging, have spurred innovation such that alternatives to the Anger Camera are now part of commercial imaging systems. Increased computing power has made it practical to apply advanced signal processing and estimation schemes to make better use of the information contained in the detector signals. In this review we discuss the key performance properties of SPECT detectors and survey developments in both scintillator and semiconductor detectors and their readouts with an eye toward some of the practical issues at least in part responsible for the continuing prevalence of the Anger Camera in the clinic.