Medium-term clinical outcomes following surgical repair for vaginal prolapse with tension-free mesh and vaginal support device
Medium-term clinical outcomes following surgical repair for vaginal prolapse with tension-free mesh and vaginal support device
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使用无张力补片和阴道支撑装置手术修复阴道脱垂后的中期临床结果
DOI：
10.1007/s00192-011-1600-3
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发表时间：
2012
影响因子：
1.8
通讯作者：
for the Glow investigators
中科院分区：
文献类型：
--
作者：
T. Sayer;J. Lim;J. Gauld;P. Hinoul;P. Jones;N. Franco;D. Drie;M. Slack;for the Glow investigators
简介和假设本研究旨在前瞻性、多中心环境中评估阴道脱垂女性接受聚丙烯网片和阴道支撑装置 (VSD) 手术后 2 年以上的临床结果。方法患者重新同意进行本次延长随访 (n = 110)，使用盆腔器官脱垂定量 (POP-Q) 进行解剖学评估，并使用经过验证的问卷来评估盆腔症状和性功能。记录并发症（安全设置；n = 121）。结果中位随访时间为 29 个月（范围 24-34 个月）。初步解剖成功率（定义为 POP-Q 0–I）为 69.1%；然而，在 84.5% 的病例中，阴道前缘位于处女膜上方。盆腔症状和性功能较基线显着改善 (p< 0.01)。网格暴露率为9.1%。 5% 的患者报告有压力性尿失禁，3.3% 的患者需要进一步进行脱垂手术。结论这些结果表明，这种非锚定网状修复术对于中期有症状的阴道脱垂女性来说是一种安全有效的治疗方法。
Introduction and hypothesisThis study was designed to evaluate clinical outcomes ≥2 years following surgery with polypropylene mesh and vaginal support device (VSD) in women with vaginal prolapse, in a prospective, multi-center setting.MethodsPatients re-consented for this extended follow-up (n = 110), with anatomic evaluation using Pelvic Organ Prolapse Quantification (POP-Q) and validated questionnaires to assess pelvic symptoms and sexual function. Complications were recorded (safety set; n = 121).ResultsMedian length of follow-up was 29 months (range 24–34 months). The primary anatomic success, defined as POP-Q 0–I, was 69.1%; however, in 84.5% of the cases, the leading vaginal edge was above the hymen. Pelvic symptoms and sexual function improved significantly from baseline (p < 0.01). Mesh exposure rate was 9.1%. Five percent reported stress urinary incontinence and 3.3% required further prolapse surgery.ConclusionThese results indicate this non-anchored mesh repair is a safe and effective treatment for women with symptomatic vaginal prolapse in the medium term.
影响因子：
120.7
作者：
Nygaard, Ingrid;Barber, Matthew D.;Burgio, Kathryn L.;Kenton, Kimberly;Meikle, Susan;Schaffer, Joseph;Spino, Cathie;Whitehead, William E.;Wu, Jennifer;Brody, Debra J.
通讯作者：
Brody, Debra J.