The carcinogenic activities in mice of compounds related to 3‐methylcholanthrene
The carcinogenic activities in mice of compounds related to 3‐methylcholanthrene
复制标题
3-甲基胆蒽相关化合物对小鼠的致癌活性
DOI：
10.1002/ijc.2910020512
复制
发表时间：
1967
影响因子：
6.4
通讯作者：
C. Beatty
中科院分区：
文献类型：
--
作者：
P. Sims;C. Beatty
A number of derivatives of 3‐methylcholanthrene have been tested for carcinogenic action by injection into C57 black mice. 1‐ and 2‐Hydroxy‐3‐methylcholanthrene and 3‐methylcholanthrene‐1‐ and 2‐one were active carcinogens, but cis‐1,2‐dihydroxy‐3‐methylcholanthrene showed only weak activity. The hydrocarbon, 3‐methylcholanthrylene (1,2‐dehydro‐3‐methylcholanthrene). was an active carcinogen. 11,12‐Epoxy‐11,12‐dihydro‐3‐methylcholanthrene showed weak carcinogenic activity whereas cis‐11,12‐dihydro‐11,12‐dihydroxy‐3‐methylcholanthrene was inactive.
