Repeated hepatectomy for colorectal metastasis.
Repeated hepatectomy for colorectal metastasis.
复制标题
因结直肠转移而重复进行肝切除术。
DOI：
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发表时间：
1997
影响因子：
0.8
通讯作者：
M. Stella
中科院分区：
文献类型：
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作者：
V. Di Carlo;P. De Nardi;G. Ferrari;P. Gini;M. Stella
1981年1月至1995年12月，12例患者，谁以前接受肝切除结直肠转移，被选为第二次肝切除孤立肝复发。第一次和第二次切除之间的平均间隔为16个月。单发8例，多发4例。2例肝大部切除术和11例楔形切除术。平均随访37个月。未观察到死亡率和33%的发病率。3年和5年精算生存率分别为71%和42%，而无病生存率为30%。没有患者、原发肿瘤或转移瘤的特征与生存率显著相关。手术切除是唯一的治疗方法，可以提供合理的机会，长期生存，并在选定的情况下，治愈。仔细选择患者以及准确的手术技术是降低术后死亡率和发病率的关键。
Between January 1981 and December 1995, 12 patients, who previously underwent hepatic resection for colorectal metastases, were selected for a second liver resection for isolated liver recurrence. Mean interval between first and second resection was 16 months. Eight patients had solitary and 4 multiple metastasis. Two major hepatectomies and 11 wedge resections were performed. Mean follow-up was 37 months. No mortality and 33% morbidity was observed. Three and 5-year actuarial survival rates were 71% and 42%, while disease-free survival was 30%. No patient, primary tumour, or metastases' characteristics were significantly associated to survival. Surgical resection is the only therapy that could offer reasonable chance of long term survival and, in selected case, of cure. A careful patients' selection as well as an accurate surgical technique are essential to reduce post operative mortality and morbidity.