Antigenic variation in the salivarian trypanosomes.
Antigenic variation in the salivarian trypanosomes.
复制标题
唾液锥虫的抗原变异。
DOI：
10.1007/978-1-4615-8855-9_4
复制
发表时间：
1977
影响因子：
--
通讯作者：
J. Doyle
中科院分区：
文献类型：
--
作者：
J. Doyle
“抗原性变异”一词被广泛用于描述这样一种现象，即在分类学上被认为是单一种致病性原生动物感染最终宿主期间，出现了一系列寄生虫种群，每个寄生虫种群被宿主的免疫反应识别为抗原性不同。这导致形成针对每个群体的特异性抗体，这可以通过识别寄生虫或被寄生细胞表面抗原的测试（如凝集和裂解）来证明。
The term “antigenic variation” has been widely used to describe a phenomenon in which, during infection of the final host by what is taxonomically considered a single species of pathogenic protozoa, there arises a succession of parasite populations, each recognized as antigenically different by the host’s immune response. This results in the formation of antibodies, specific for each population, which are demonstrable by tests recognizing surface antigens of the parasite or parasitized cell such as agglutination and lysis.