Highland malaria in Uganda: prospective analysis of an epidemic associated with El Nino

Highland malaria in Uganda: prospective analysis of an epidemic associated with El Nino
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DOI:
10.1016/s0035-9203(99)90344-9
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发表时间:
1999-09-01
影响因子:
2.2
通讯作者:
Wilson, ML
Wilson, ML
中科院分区:
医学4区
文献类型:
--
作者:
Lindblade, KA;Walker, ED;Wilson, ML

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非洲高地的疟疾流行病造成严重的发病率和死亡率,而且报告的频率越来越高。天气可能在引发流行病方面发挥重要作用,但对天气条件与流行病传播参数之间的关系进行了有限的分析。我们在乌干达西南部一个高原地区疟疾流行(始于1998年2月)之前和期间测量了昆虫学变量,并分析了天气数据与疟疾发病率(根据诊所记录估计)、蚊子密度和昆虫学接种率(EIR)的时间变化。冈比亚按蚊室内静息密度与疟疾发病率呈正相关(r = 0.68, P
Malaria epidemics in African highlands cause serious morbidity and mortality and are being reported more frequently. Weather is likely to play an important role in initiating epidemics but limited analysis of the association between weather conditions and epidemic transmission parameters has been undertaken. We measured entomological variables before and during an epidemic of malaria (which began in February 1998) in a highland region of south-western Uganda and analysed temporal variation in weather data against malaria incidence (estimated from clinic records), mosquito density and entomological inoculation rates (EIR). Indoor resting density of Anopheles gambiae s.l. was positively correlated with malaria incidence (r = 0.68, P