THE ROLE OF ELASTIN IN THE MECHANICAL-PROPERTIES OF SKIN
THE ROLE OF ELASTIN IN THE MECHANICAL-PROPERTIES OF SKIN
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DOI：
10.1016/0021-9290(88)90172-8
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发表时间：
1988-01-01
影响因子：
2.4
通讯作者：
VIIDIK, A
中科院分区：
文献类型：
--
作者：
OXLUND, H;MANSCHOT, J;VIIDIK, A
在大鼠皮肤标本中加入大豆抑制剂，用弹性蛋白酶的纯化制剂降解弹性蛋白纤维，以防止弹性酶对胶原的降解活性。对照实验确定了弹性蛋白的降解，而对胶原没有影响。研究了酶处理前后皮肤样品的力学性能，并将差异归因于降解的弹性蛋白纤维。弹性蛋白在小应力值和小变形时对大鼠皮肤的力学行为起作用。特别是在施加应力或变形后，弹性蛋白纤维负责回弹机制。
The elastin fibers of rat skin samples were degraded by the use of a purified preparation of elastase to which soybean inhibitor was added, preventing the collagenolytic activity of the elastase on collagen. Control experiments ascertained degradation of elastin and no effect on collagen. The mechanical properties of the skin samples were studied before and after the enzymatic treatment and differences ascribed to the degraded elastin fibers. Elastin plays a role in the mechanical behaviour of rat skin at small stress values and small deformations. Especially, the elastin, fibers are responsible for the recoiling mechanism after a stress or deformation has been applied.