Miscibility behavior of two-component monolayers at the air-water interface: perfluorocarboxylic acids and DMPE.
Miscibility behavior of two-component monolayers at the air-water interface: perfluorocarboxylic acids and DMPE.
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DOI：
10.1016/j.jcis.2009.05.010
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发表时间：
2009-09
影响因子：
9.9
通讯作者：
H. Yokoyama;H. Nakahara;T. Nakagawa;Satoshi Shimono;K. Sueishi;O. Shibata
中科院分区：
文献类型：
--
作者：
H. Yokoyama;H. Nakahara;T. Nakagawa;Satoshi Shimono;K. Sueishi;O. Shibata
测量了四种不同的全氟羧酸[FCn]的双组分单层的表面压力(π) -分子面积(A)和表面电位（ΔV） -等温线；全氟十二烷酸（FC12）、全氟十四烷酸（FC14）、全氟十六烷酸（FC16）、全氟十八烷酸（FC18）]和二myristoylphosphatidyethanol amine （DMPE）在0.15M NaCl （pH 2）和298.2 2k条件下。本文主要研究了二元DMPE/FCn单层压缩时的混相和界面行为。从等温线出发，从可加性规则、相互作用参数和相互作用能三个方面对混相性进行了解释。将相互作用参数（或能量）与先前的双棕榈酰磷脂酰胆碱(DPPC)/FCn体系[Colloids Surf]进行了比较。B 41(2005) 285-298]以了解磷脂极性头基对二元混相的影响。此外，使用荧光显微镜（FM）和原子力显微镜（AFM）对DMPE/FCn体系的相行为进行了形态学检查。这些图像揭示了四个系统之间不同的相互作用模式；DMPE在单层状态下可与FC12、FC14混溶，与FC16、FC18不混溶。这些系统的检验表明，全氟羧酸和磷脂的混溶性取决于碳氢化合物和碳氟化合物链长度的组合以及单层内磷脂的极性头基。
Surface pressure (π)–molecular area (A) and surface potential (ΔV)–A isotherms have been measured for two-component monolayers of four different perfluorocarboxylic acids [FCn; perfluorododecanoic acid (FC12), perfluorotetradecanoic acid (FC14), perfluorohexadecanoic acid (FC16), and perfluorooctadecanoic acid (FC18)] and dimyristoylphosphatidylethanolamine (DMPE) on 0.15M NaCl (pH 2) at 298.2K. The present study is focused on the miscibility and the interfacial behavior for the binary DMPE/FCn monolayers upon compression. From the isotherms, the miscibility has been elucidated in terms of the additivity rule, the interaction parameter, and the interaction energy. The interaction parameter (or energy) is compared with that for the previous dipalmitoylphosphatidylcholine (DPPC)/FCn systems [Colloids Surf. B 41 (2005) 285–298] to understand the effect of phospholipids’ polar headgroup on the binary miscibility. Furthermore, the phase behavior of the DMPE/FCn systems has been morphologically examined using fluorescence microscopy (FM) and atomic force microscopy (AFM). These images reveal the different interaction modes among the four systems; DMPE can be miscible with FC12 and FC14 and immiscible with FC16 and FC18 in the monolayer state. These systematic examinations indicate that the miscibility of perfluorocarboxylic acids and phospholipids depends on combination of hydrocarbon and fluorocarbon chain lengths and on phospholipids’ polar headgroups within a monolayer.