Maxikdiol: a novel dihydroxyisoprimane as an agonist of Maxi-K channels

Maxikdiol: a novel dihydroxyisoprimane as an agonist of Maxi-K channels
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Maxikdiol:一种新型二羟基异伯烷,作为 Maxi-K 通道的激动剂

DOI:
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发表时间:
1994
期刊:
影响因子:
--
通讯作者:
G. Kaczorowski
G. Kaczorowski
中科院分区:
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文献类型:
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作者:
Suresh B. Singh;M. Goetz;D. Zink;A. Dombrowski;J. Polishook;Maria L. Garcia;W. Schmalhofer;O. McManus;G. Kaczorowski

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Maxi-K(大电导钙激活钾)通道是一类被认为在控制气道平滑肌收缩中起重要作用的蛋白质家族。Maxikdiol是一种新型的1,5-二羟基异丙三胺二萜类化合物,具有通道激动剂的作用。本文介绍了麦西克二醇的分离、结构鉴定和生物活性。
Maxi-K (large-conductance calcium-activated potassium)channels are a family of proteins which are thought to play an important role in controlling the contractility of airway smooth muscle. Maxikdiol is a novel, 1,5-dihydroxyisoprimane, diterpenoid which acts as an agonist of the channel. The isolation, structure elucidation and biological activity of maxikdiol are described.
乙醇调节[125I]钙调蛋白与大鼠脑突触质膜的结合。
DOI: --
发表时间: 1994
期刊: The Journal of pharmacology and experimental therapeutics
影响因子: --
作者:
Sze,PY;Iqbal,Z
通讯作者: Iqbal,Z