A new inorganic photolabile protecting group for highly efficient visible light GABA uncaging
A new inorganic photolabile protecting group for highly efficient visible light GABA uncaging
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DOI：
10.1002/cbic.200700354
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发表时间：
2007-11-23
期刊：
影响因子：
3.2
通讯作者：
Etchenique, Roberto
中科院分区：
文献类型：
--
作者：
Zayat, Leonardo;Noval, Maria G.;Etchenique, Roberto
制备了抑制性神经递质 γ-氨基丁酸 (GABA) 的无机笼化合物，并通过 450 nm 光进行光解，具有迄今为止报道的最高解笼量子产率。使用这种笼状化合物在生物制品中通过辐射激活 GABA 离子通道。
An inorganic-based caged compound of the inhibitory neurotransmitter, gamma-amino butyric acid (GABA), was prepared and photolysed by light at 450 nm with the highest uncaging quantum yield reported to date. GABA ion channels were activated by irradiation in a biological preparation by using this caged compound.