Developmental Delay in Moderately Preterm-Born Children at School Entry
Developmental Delay in Moderately Preterm-Born Children at School Entry
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DOI：
10.1016/j.jpeds.2010.12.041
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发表时间：
2011-07-01
影响因子：
5.1
通讯作者：
Bos, Arend F.
中科院分区：
文献类型：
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作者：
Kerstjens, Jorien M.;de Winter, Andrea F.;Bos, Arend F.
目的探讨中度早产儿与足月早产儿和早期早产儿学龄前发育迟缓的发生率和性质。研究设计：927例中度早产儿（孕32-35（+）6周），512例早期早产儿（低于平均值2个标准差）ASQ总分在中度早产儿、足月儿和早期早产儿中分别为8.3%、4.2%和14.9%。中度早产儿ASQ总分异常的OR为2.1（95%CI，1.3-3.4），早期早产儿为4.0（95%CI，2.4-6.5）。与足月儿相比，中度和早期早产儿在精细运动、沟通和个人社会功能方面的问题更常见。与足月儿相比，中度早产儿在粗大运动功能和问题解决方面的问题发生率并不高，而早期早产儿则高。社会经济地位，小于胎龄状态，性别与异常ASQ评分中度早产birth.Conclusions在学龄前，中度早产儿的发育迟缓的患病率是2倍，在足月婴儿和一半，在早期早产儿。（J Pediatr 2011;159：92-8）。
Objective To determine the prevalence and nature of developmental delay at preschool age in infants born moderately preterm compared with those born full-term and early preterm.Study design Parents of 927 moderate preterm infants (32-35(+) 6 weeks gestation), 512 early preterm infants (2 SDs below the mean) ASQ total scores were noted in 8.3% of moderate preterm infants, in 4.2% of full-term infants, and in 14.9% of early preterm infants. ORs of abnormal ASQ total scores were 2.1 (95% CI, 1.3-3.4) for moderate preterm infants and 4.0 (95% Cl, 2.4-6.5) for early preterm infants. Both moderate and early preterm infants had more frequent problems with fine motor, communication, and personal-social functioning compared with full-term infants. Compared with full-term infants, moderate preterm infants did not have a greater prevalence of problems with gross motor functioning and problem solving, whereas early preterms did. Socioeconomic status, small for gestational age status, and sex were associated with abnormal ASQ scores in moderate preterm infants.Conclusions At preschool age, the prevalence of developmental delay in moderate preterm infants was 2-fold of that in full-term infants and one-half of that in early preterm infants. (J Pediatr 2011;159:92-8).