Bone remodelling after regenerative procedures around implants placed in fresh extraction sockets: an experimental study in Beagle dogs (Retracted article. See vol. 29, pg. 539, 2018)
Bone remodelling after regenerative procedures around implants placed in fresh extraction sockets: an experimental study in Beagle dogs (Retracted article. See vol. 29, pg. 539, 2018)
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DOI：
10.1111/j.1600-0501.2010.02084.x
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发表时间：
2011-10-01
影响因子：
4.3
通讯作者：
Covani, U.
中科院分区：
文献类型：
--
作者：
Barone, A.;Ricci, M.;Covani, U.
简介：拔牙后，颊壁的高度往往会降低。文献表明再生技术（引导骨再生[GBR]技术）已成功改善骨水平。因此，本实验旨在比较在新鲜拔牙槽中植入种植体后，在应用和不应用再生程序的情况下比格犬模型中的生理性骨重塑。材料和方法：本研究使用了五只狗。随机选择测试和对照地点。将实验牙齿（第四前磨牙和第一磨牙）半切开，去除远端牙根并放置种植体。放置猪骨以填充测试部位的植入物周围的间隙，并使用可吸收膜覆盖该区域。这些狗在不同时间（2周、1个月和3个月）被安乐死。测量立即进行，并在种植体植入后 2、4、12 周进行。配对数据的学生测试用于比较临床测量的平均值。结果：第 2 周时：在对照部位上，仅在第一磨牙处检测到少量吸收迹象，而在测试部位上，骨水平位于种植体肩部或以上。第 4 周时：在对照部位上，观察到轻微的骨重塑，而在测试部位上，检测到轻微的吸收迹象或骨水平增加。第 12 周时：对照部位上的牙槽嵴显示出不同程度的改造。在测试部位观察到骨水平稳定或骨嵴增加。结论：在本研究的限制下，研究结果表明GBR技术能够限制拔牙后牙槽嵴的吸收。在对照部位（无GBR）和测试部位（GBR）中观察到拔牙和种植体植入后的骨重塑模式，尽管其确切原因尚不清楚，但手术创伤可能发挥了作用。需要进一步的研究来证实这些结果并阐明新鲜拔牙槽中骨重塑的确切原因。
Introduction: After a tooth extraction, the height of the buccal wall tends to decrease. The literature indicates that regenerative techniques (guided bone regenerative [GBR] techniques) have succeeded in improving the bone levels. Therefore, this experiment set out to compare the physiological bone remodelling in Beagle dog models after implant placement in a fresh extraction socket, with and without the application of regenerative procedure.Materials and methods: Five dogs were used in this study. Test and control sites were randomly selected. The experimental teeth (fourth pre-molar and first molar) were hemi-sected removing the distal roots and placing implants. Porcine bone was placed to fill the gap around the implant on the test sites and a reabsorbable membrane was used to cover the area. The dogs were put down at different times (2 weeks, 1 month and 3 months). The measurements were taken immediately and at 2, 4, 12 weeks after implant placement. Student's test for paired data was used to compare the means of the clinical measurements.Results: At 2 weeks: On the control sites, few signs of resorption were detected at the first molar only, while at the test sites bone levels were placed at the implant shoulder or above.At 4 weeks: On the control site, slight bone remodelling was observed, while on the test site minor signs of resorption or an increase of bone levels were detected.At 12 weeks: The alveolar crest on the control sites showed various degrees of remodelling. On the test sites stable bone levels or an increase of bone crest was observed.Conclusion: With the limits of this study, the findings showed that GBR techniques were able to limit resorption of the alveolar crest after tooth extraction. A pattern of bone remodelling after tooth extraction and implant placement was observed in the control sites (no GBR) as well as in test sites (GBR), and although the exact cause of this is unclear, surgical trauma could play a role. Further studies are necessary to confirm these results and to clarify the precise causes of bone remodelling in fresh extraction sockets.