Effect of Treatment with Growth Hormone on Somatostatin in the Median Eminence of Hypophysectomized Rats 1 2

Effect of Treatment with Growth Hormone on Somatostatin in the Median Eminence of Hypophysectomized Rats 1 2
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生长激素治疗对垂体切除大鼠中位隆起生长抑素的影响 1 2

DOI:
10.3181/00379727-156-39919
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发表时间:
1977
影响因子:
--
通讯作者:
Burton L. Baker
Burton L. Baker
中科院分区:
--
文献类型:
--
作者:
D. Hoffman;Burton L. Baker

文献摘要

被引文献

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生长激素治疗部分阻止了大鼠在切除垂体后立即开始治疗时正中隆起生长抑素的耗竭,并在延长垂体切除后间隔时间后开始治疗时部分恢复生长抑素。这些观察表明,生长激素倾向于增加生长抑素在正中隆起的储存。
Summary Treatment of rats with growth hormone partially prevented depletion of somatostatin from the median eminence when therapy was begun immediately following hypophysectomy, and partially restored somatostatin when treatment was initiated after a prolonged posthypophysec-tomy interval. These observations suggest that growth hormone tends to increase the store of somatostatin in the median eminence.