Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab)
Health behaviours, socioeconomic status and diabetes incidence: the Australian Diabetes Obesity and Lifestyle Study (AusDiab)
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DOI：
10.1007/s00125-010-1888-4
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发表时间：
2010-12-01
期刊：
影响因子：
8.2
通讯作者：
Oldenburg, B. F.
中科院分区：
文献类型：
--
作者：
Williams, E. D.;Tapp, R. J.;Oldenburg, B. F.
目的/假设要确定的影响，社会经济地位的事件糖代谢受损和2型糖尿病，并探讨这种关系使用国家，人口为基础的data.Methods的健康行为的中介作用，澳大利亚糖尿病肥胖和生活方式（AusDiab）研究是一个国家，人口为基础的，纵向研究的成年人年龄在25岁及以上。共有4，405人的样本提供了与这些分析相关的完整基线（1999-2000年）和5年随访（2004-2005年）数据。通过OGTT获得空腹血糖和2 h血糖，并通过访谈和问卷调查收集人口统计学、社会经济学和行为学数据。多项逻辑回归研究的社会经济地位的作用，在糖尿病的发展和调解分析测试的贡献，健康的行为，在此relationship.Results最高水平的教育是一个较强的预测事件糖耐量减低和2型糖尿病（P=0.002），家庭收入（P=0.103），职业等级（P=0.202）。在完全调整的模型中，教育仍然是糖尿病的重要独立预测因素。然而，健康行为（吸烟和体育活动）削弱了这种关系。调解分析表明，这些行为是部分调解人（解释27%）的社会经济地位，糖尿病relationship.Conclusion/interpretation吸烟和体力活动部分调解低教育和2型糖尿病之间的关系。这些可改变的行为介质的识别应促进有效的健康促进运动的发展，以针对那些发展为2型糖尿病的高风险。
Aims/hypothesis To identify the impact of socioeconomic status on incident impaired glucose metabolism and type 2 diabetes and to investigate the mediating role of health behaviours on this relationship using national, population-based data.Methods The Australian Diabetes Obesity and Lifestyle (AusDiab) Study is a national, population-based, longitudinal study of adults aged 25 years and above. A total sample of 4,405 people provided complete baseline (1999-2000) and 5 year follow-up (2004-2005) data relevant for these analyses. Fasting plasma glucose and 2 h plasma glucose were obtained from an OGTT, and demographic, socioeconomic and behavioural data were collected by interview and questionnaire. Multinomial logistic regression examined the role of socioeconomic position in the development of diabetes and mediation analyses tested the contribution of health behaviours in this relationship.Results Highest level of education was a stronger predictor of incident impaired glucose tolerance and type 2 diabetes (p=0.002), compared with household income (p=0.103), and occupational grade (p=0.202). Education remained a significant independent predictor of diabetes in fully adjusted models. However, the relationship was attenuated by the health behaviours (smoking and physical activity). Mediation analyses indicated that these behaviours were partial mediators (explaining 27%) of the socioeconomic status-diabetes relationship.Conclusion/interpretation Smoking and physical activity partly mediate the relationship between low education and type 2 diabetes. Identification of these modifiable behavioural mediators should facilitate the development of effective health promotion campaigns to target those at high risk of developing type 2 diabetes.