Late-Onset Radiation-Induced Vasculopathy and Stroke in a Child With Medulloblastoma

Late-Onset Radiation-Induced Vasculopathy and Stroke in a Child With Medulloblastoma
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DOI:
10.1177/0883073814538501
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发表时间:
2015-05-01
影响因子:
1.9
通讯作者:
Zuccoli, Giulio
Zuccoli, Giulio
中科院分区:
医学4区
文献类型:
--
作者:
Bansal, Lalit R.;Belair, Jeffrey;Zuccoli, Giulio

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我们报告一个15岁的男孩谁提出了我们的机构与左侧无力和言语不清的情况。他有髓母细胞瘤病史,在3岁时诊断,术后切除和颅脊髓放射治疗。脑部磁共振成像(MRI)显示右侧旁正中脑桥梗死,疑似继发于迟发性辐射诱导的椎基底动脉系统血管病变。脑辐射与缺血性中风的发病率增加有关。当这些患者出现新的神经系统症状时,临床医生应高度怀疑卒中。
We report a case of a 15-year-old boy who presented to our institution with left-sided weakness and slurred speech. He had a history of medulloblastoma diagnosed at 3 years of age, status postsurgical resection and craniospinal radiation. Magnetic resonance imaging (MRI) of brain revealed a right paramedian pontine infarction, suspected secondary to late-onset radiation-induced vasculopathy of the vertebrobasilar system. Radiation to the brain is associated with increased incidence of ischemic stroke. Clinicians should have a high index of suspicion for stroke when these patients present with new neurologic symptoms.