Suboptimal immune recovery and associated factors among people living with HIV/AIDS on second-line antiretroviral therapy in central China: A retrospective cohort study
Suboptimal immune recovery and associated factors among people living with HIV/AIDS on second-line antiretroviral therapy in central China: A retrospective cohort study
复制标题
中国中部地区接受二线抗逆转录病毒治疗的艾滋病毒/艾滋病患者免疫恢复不佳及相关因素：一项回顾性队列研究
DOI：
10.1002/jmv.27944
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发表时间：
2022-07-10
影响因子：
12.7
通讯作者：
Jin, Yantao
中科院分区：
文献类型：
--
作者：
Zhu, Keying;Xu, Qianlei;Jin, Yantao
抗逆转录病毒疗法的采用和推广，大大改善了艾滋病患者的生活质量，提高了他们的生存率。这是通过抑制病毒复制和恢复CD 4细胞计数来实现的。然而，尽管病毒载量（VL）受到抑制，但一些患者的CD 4细胞计数并未正常化。免疫恢复欠佳（SIR）的患者，定义为VL < 400拷贝/ml，CD 4细胞计数<
The introduction and scale-up of antiretroviral therapy (ART) have contributed to significantly improved patients with acquired immune deficiency syndrome (AIDS) quality of life and prolongs their survival. This has occurred by suppressing viral replication and recovering the CD4 cell count. However, some patients do not normalize their CD4 cell count, despite suppression of the viral load (VL). Patients with suboptimal immune recovery (SIR), as defined by a VL < 400 copies/ml with a CD4 cell count of