Association Between Red Blood Cell Distrbution Width and Prognosis of Renal Transplant Recipients with Early-Onset Pneumonia
Association Between Red Blood Cell Distrbution Width and Prognosis of Renal Transplant Recipients with Early-Onset Pneumonia
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红细胞分布宽度与肾移植受者早发性肺炎预后的关系
DOI：
10.12659/msm.917841
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发表时间：
2019-09-04
影响因子：
3.1
通讯作者：
Liu, Hong
中科院分区：
文献类型：
--
作者：
Ming, Yingzi;Yang, Min;Liu, Hong
背景：肾移植术后，早发性肺炎是一种常见且严重的感染相关并发症。红细胞分布宽度（RDW）已被报道为传染病患者的预测指标。因此，本研究的目的是探讨RDW在预测肾移植受者早发性肺炎的预后（包括60天死亡率）中的意义。材料/方法：回顾性分析肾移植术后发生早发性肺炎患者的临床资料。患者分为两组：RDW为15.0%。采用Kaplan-Meier方法估计60天死亡率、菌血症、机械通气需求、肾移植排斥率和入住重症监护病房（ICU）的人数。进行单因素和多因素Cox回归分析以确定60天死亡率的危险因素。结果：参与研究的118例患者中，18例（15.2%）在60天随访期间死亡。Kaplan-Meier分析显示，组内死亡率为9.38%，RDW为15.0% (P
Background: Following renal transplantation, early-onset pneumonia is a frequent and severe infection-related complication. Red blood cell distribution width (RDW) has been reported as a predictive marker among patients with infectious diseases. Therefore, the aim of this study was to explore the significance of RDW in predicting prognosis, including 60-day mortality, in renal transplant recipients with early-onset pneumonia.Material/Methods: Clinical data from patients who developed early-onset pneumonia after renal transplantation were retrospectively reviewed. Patients were divided into 2 groups: those with an RDW 15.0%. The 60-day mortality, bacteremia, need for mechanical ventilation, renal transplant rejection rate, and number of admissions to the intensive care unit (ICU) were estimated by Kaplan-Meier methods. Univariate and multivariate Cox regression analyses were performed to determine the risk factors for 60-day mortality.Results: Among the 118 patients participating in the study, 18 (15.2%) died during the 60-day follow-up. Kaplan-Meier analysis showed a death rate of 9.38% in the group with an RDW 15.0% (P