Clinical significance of Corynebacterium striatum isolated from human samples.
Clinical significance of Corynebacterium striatum isolated from human samples.
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DOI：
10.1111/j.1469-0691.1997.tb00470.x
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发表时间：
1997-02-01
期刊：
影响因子：
--
通讯作者：
Muniain, M. A.
中科院分区：
文献类型：
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作者：
Martinez-Martinez, L.;Suarez, A.I.;Muniain, M. A.
目的：探讨纹状棒状杆菌感染的临床意义和相关因素。方法：对1991年1月至1995年7月在某大学医院分离的纹状体进行回顾性分析。采用常规方法、API CORYNE系统和细胞脂肪酸谱对纹状体进行鉴定。结果：在研究期间，从127例患者的临床标本中分离到纹状体梭菌。在49例患者中，临床图表的数据被认为不足以进行评估。在26例中，微生物被认为是感染过程的病原。在剩下的52名患者中，这种微生物被认为是一个定植者。所有患者在感染前均因某种基础疾病住院，其中22例（85%）既往接受过抗生素治疗。6名患者死亡。其中两人的死亡是其潜在疾病的结果，其余4人的死亡与纹状体梭状体感染有关。结论：纹状梭菌是一种传统上被认为是正常人鼻咽和皮肤菌群中无毒的微生物，它可能会在有基础疾病和既往接受过抗生素治疗的住院患者中引起感染。
OBJECTIVE: To evaluate the clinical significance of and describe factors associated with Corynebacterium striatum infection. METHODS: A retrospective chart review was performed of the C. striatum isolated in a university hospital from January 1991 to July 1995. C. striatum was identified using conventional methods, the API CORYNE system and cellular fatty acid profiles. RESULTS: In the study period, C. striatum was isolated from clinical samples in 127 patients. In 49 patients, data from clinical charts were considered insufficient for evaluation. In 26 cases, the microorganism was considered to be the etiologic agent of an infectious process. In the remaining 52 patients, the organism was considered to be a colonizer. Before the infection all the patients had been hospitalized for some underlying condition, and 22 (85%) of them had received antibiotics previously. Six patients died. In two of them, death was a consequence of their underlying disease and in the remaining four, death was related to the C. striatum infection. CONCLUSIONS: C. striatum, a microorganism traditionally considered to be an avirulent member of the normal human nasopharyngeal and skin flora, may opportunistically cause infections in hospitalized patients with underlying diseases and previous antibiotic treatments.