Development and Phantom Validation of a 3-D-Ultrasound-Guided System for Targeting MRI-Visible Lesions During Transrectal Prostate Biopsy.
Development and Phantom Validation of a 3-D-Ultrasound-Guided System for Targeting MRI-Visible Lesions During Transrectal Prostate Biopsy.
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DOI：
10.1109/tbme.2016.2582734
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发表时间：
2017-04
期刊：
影响因子：
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通讯作者：
Barratt DC
中科院分区：
文献类型：
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作者：
Hu Y;Kasivisvanathan V;Simmons LA;Clarkson MJ;Thompson SA;Shah TT;Ahmed HU;Punwani S;Hawkes DJ;Emberton M;Moore CM;Barratt DC
三维和四维经直肠超声换能器现在可以从大多数主要的超声设备制造商获得，但目前只被整合到一个商业前列腺活检引导系统中。这种传感器具有快速体积成像的优点，但可能会在电磁跟踪传感器中造成严重的测量失真，电磁跟踪传感器通常用于实现3D导航。在本文中，我们描述了一种3D超声引导的经直肠前列腺活检系统的设计、开发和验证，该系统使用高精度的光学跟踪来在3D物理空间中定位超声探头和前列腺靶。通过使用标准2D超声引导和新系统提供的实时3D引导，在模体中插入活检针以采样计划目标后，通过评估目标针放置误差来验证系统的准确性。针与靶的总距离误差为3.6±4.0 mm，针与靶的距离为3.2±2.4 mm。与使用标准B型超声引导活检技术的不可见(虚拟)病变的视觉定位相比，使用3D引导系统时，针放置的准确性显著提高。
Three- and four-dimensional transrectal ultrasound transducers are now available from most major ultrasound equipment manufacturers, but currently are incorporated into only one commercial prostate biopsy guidance system. Such transducers offer the benefits of rapid volumetric imaging, but can cause substantial measurement distortion in electromagnetic tracking sensors, which are commonly used to enable 3D navigation. In this paper, we describe the design, development and validation of a 3D-ultrasound-guided transrectal prostate biopsy system that employs high-accuracy optical tracking to localize the ultrasound probe and prostate targets in 3D physical space. The accuracy of the system was validated by evaluating the targeted needle placement error after inserting a biopsy needle to sample planned targets in a phantom using standard 2D ultrasound guidance versus realtime 3D guidance provided by the new system. The overall mean needle-segment-to-target distance error was 3.6±4.0 mm and mean needle-to-target distance was 3.2±2.4 mm. a significant increase in needle placement accuracy was observed when using the 3D guidance system compared with visual targeting of invisible (virtual) lesions using a standard B-mode ultrasound guided biopsy technique.