CORTICAL BONE SENESCENCE AND MINERAL BONE-DENSITY OF THE HUMERUS
CORTICAL BONE SENESCENCE AND MINERAL BONE-DENSITY OF THE HUMERUS
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DOI：
10.1007/bf02405044
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发表时间：
1983-01-01
影响因子：
4.2
通讯作者：
GARCIASCHAEFER, F
中科院分区：
文献类型：
--
作者：
LAVALJEANTET, AM;BERGOT, C;GARCIASCHAEFER, F
对89例急性身体的肱骨皮质的研究表明，增龄引起生理性骨丢失的一个重要因素是骨孔率增加。男性和女性的平均皮质孔隙率随着年龄的增长而增加，从40岁时男性的4.6%和女性的4%增加到80岁时的10%或更多。在被研究的人群中，男性和女性之间的孔隙率没有显著差异。表观矿物质密度与孔隙度有关，在女性中，随着年龄的增长，表观矿物质密度显著下降。男性的变化幅度较小，表现出密度值的较大差异。通过反映皮质骨中血管和吸收空间比例的系数对表观矿物质密度进行校正，得到的真实矿物质密度不会随着年龄的增长而显著变化，无论性别。所获得的肱骨近端密度值与文献中代表股骨的密度值不同。然而，它们更容易与临床密度测量的结果相比较，并可能有更大的临床应用。
Study of the humeral cortex of 89 acute cadavers showed that an important factor contributing to the physiologic bone loss of aging is increasing bone porosity. Mean cortical porosity increases in both sexes with age, from 4.6% in men and 4% in women at 40 yr of age to 10% and more at age 80. In the population studied, no significant difference of porosity was observed between men and women. Apparent mineral density is linked to porosity and decreases markedly with age in women. Changes in men are lesser in magnitude and show a larger difference of density values. Correction of the apparent mineral density, by a factor reflecting the proportion of vascular and resorption spaces in the cortical bone, produces a true mineral density which does not vary significantly with age in either sex. The density values obtained for the proximal humerus differ from those in the literature which represent the femur. However, they are more readily compared with the results of clinical densitometry and may have greater clinical applications.