Meningococcal disease in Asia: an under-recognized public health burden.
Meningococcal disease in Asia: an under-recognized public health burden.
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DOI：
10.1017/s0950268811000574
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发表时间：
2011-07
影响因子：
4.2
通讯作者：
Soriano-Gabarro, M.
中科院分区：
文献类型：
--
作者：
Vyse, A.;Wolter, J. M.;Chen, J.;Ng, T.;Soriano-Gabarro, M.
关键词：
文献检索追踪了亚洲脑膜炎球菌病的现有信息。描述亚洲脑膜炎球菌病流行病学的审查数据不完整，部分原因是许多国家缺乏监测，细菌检测方法差以及疾病报告的社会和医疗障碍。这表明，一些亚洲国家对脑膜炎球菌病的认识可能不足，需要采用/改进现有的监测和病例识别系统。然而，在一些亚洲发展中国家，疾病负担可能很重。血清群A脑膜炎球菌流行病是一些国家发病率和死亡率高的原因，并继续是一个持续的威胁，特别是在发展中国家。血清群C、Y和W-135在侵袭性疾病中发挥的作用越来越大，表明脑膜炎球菌病在一些国家的流行病学正在演变。多价脑膜炎球菌结合疫苗为该区域减少脑膜炎球菌疾病负担提供了新的机会。
A literature search traced existing information on meningococcal disease in Asia. Reviewed data describing the epidemiology of meningococcal disease in Asia are incomplete, due in part to absence of surveillance in many countries, poor bacterial detection methods and social and healthcare barriers to disease reporting. This suggests that meningococcal disease in some Asian countries may be under-recognized, with a need to introduce/improve existing surveillance and case identification systems. Nevertheless, in some developing Asian countries, the disease burden may be significant. Serogroup A meningococcal epidemics are responsible for high morbidity and mortality in some countries and continue to be an ongoing threat, particularly in developing countries. There is an increasing role played by serogroups C, Y, and W-135 in invasive disease, indicating evolving meningococcal disease epidemiology in some countries. Multivalent meningococcal conjugate vaccines offer new opportunities in the region for reducing the meningococcal disease burden.