Astaxanthin improves the developmental competence of invitro-grown oocytes and modifies the steroidogenesis of granulosa cells derived from bovine early antral follicles
Astaxanthin improves the developmental competence of invitro-grown oocytes and modifies the steroidogenesis of granulosa cells derived from bovine early antral follicles
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DOI：
10.1071/rd17527
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发表时间：
2019-01-01
影响因子：
1.9
通讯作者：
Nagano, M.
中科院分区：
文献类型：
--
作者：
Abdel-Ghani, M. A.;Yanagawa, Y.;Nagano, M.
在这项研究中，我们研究了虾青素（Ax），这表现出很强的抗氧化活性，在体外生长（IVG）的卵母细胞的发育能力和早期窦卵泡颗粒细胞的类固醇合成的影响。牛卵母细胞-卵丘-颗粒复合物收集早期窦卵泡培养12天，在存在或不存在（对照）的500 μ M Ax。在IVG培养过程中，有Ax存在时卵母细胞的存活率和颗粒细胞层的腔形成率高于无Ax存在时（P
In this study we investigated the effect of astaxanthin (Ax), which exhibits strong antioxidant activity, during invitro growth (IVG) on the developmental competence of oocytes and steroidogenesis of granulosa cells derived from early antral follicles. Bovine oocyte-cumulus-granulosa complexes collected from early antral follicles were cultured for 12 days in the presence or absence (control) of 500 mu M Ax. The viability of oocytes and antrum formation in the granulosa cell layer during IVG culture were greater in the presence than absence of Ax (P