Inflammation and immune evasion coexist in Treponema pallidum-infected skin.
Inflammation and immune evasion coexist in Treponema pallidum-infected skin.
复制标题
炎症和免疫逃避在梅毒螺旋体感染的皮肤中并存。
DOI：
10.1016/j.jdcr.2018.03.011
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发表时间：
2018
影响因子：
--
通讯作者：
Salazar,JuanC
中科院分区：
文献类型：
--
作者：
Trujillo,Rodolfo;Cervantes,Jorge;Hawley,KellyL;Cruz,AdrianaR;Babapoor,Sankhiros;Murphy,Michael;Dadras,SoheilS;Salazar,JuanC
ConclusionsSecondary syphilitic lesions can sometimes be overlooked and misdiagnosed. The lesions on the neck of our patient could be confused with psoriatic lesions or scar tissue. On the other hand, the involvement of palms and soles suggest that this patient has SS (Figs 2 and 3). Silver stains and immunohistochemical analysis can highlight spirochetes in lesions of cutaneous SS, like the ones shown in Fig 1. Our findings by IF provide evidence that the spirochetal burden is probably greater than can be determined using traditional histologic techniques. These lesions have the capability of being extremely infectious, especially if the appropriate circumstances are present, such as intimate contact and skin laceration. 2
