Intergenerational predictors of diurnal cortisol secretion in early childhood
Intergenerational predictors of diurnal cortisol secretion in early childhood
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DOI：
10.1002/icd.474
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发表时间：
2007-03-01
影响因子：
2.2
通讯作者：
Schwartzman, Alex E.
中科院分区：
文献类型：
--
作者：
Ben-Dat Fisher, Dahlia;Serbin, Lisa A.;Schwartzman, Alex E.
本研究探讨了可能导致幼儿期皮质醇昼夜分泌非典型模式的潜在代际联系。唾液皮质醇样本收集在1个清醒的一天，在36个学龄前儿童的母亲是一个正在进行的纵向项目的参与者。分层线性模型（HLM）确定了每日皮质醇轨迹的个体差异的统计学显着预测。儿童表现出相对较低的觉醒后值和平坦的皮质醇轨迹在一天中作为一个功能的不支持的母亲的行为，二手烟和母亲的历史，在童年的社会退缩。这些结果表明，幼儿的昼夜皮质醇模式的个体差异与各种当前和历史的母亲的特征和行为。儿童的昼夜神经内分泌功能的代际预测的识别可能会提供新的见解从父母到孩子的健康和发育风险的转移。版权所有（c）2007约翰威利父子有限公司。
The present study examined potential intergenerational links that may contribute to atypical patterns of diurnal cortisol secretion in early childhood. Salivary cortisol samples were collected across 1 waking day in 36 pre-school children whose mothers are participants in an ongoing longitudinal project. Hierarchical Linear Modeling (HLM) identified statistically significant predictors of individual differences in daily cortisol trajectories. Children displayed relatively low post-awakening values and flatter cortisol trajectories across the day as a function of unsupportive maternal behaviour, second-hand smoke and maternal histories of social withdrawal in childhood. These results suggest that individual differences in young children's pattern of diurnal cortisol are associated with a variety of current and historical maternal characteristics and behaviours. The identification of intergenerational predictors of children's diurnal neuroendocrine functioning may provide new insights into the transfer of health and developmental risk from parent to child. Copyright (c) 2007 John Wiley & Sons, Ltd.