Progress in the Synthesis of N-Acyl-N,O-acetals
Progress in the Synthesis of N-Acyl-N,O-acetals
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DOI：
10.1055/a-1684-0772
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Xingyong Liu
中科院分区：
文献类型：
--
作者：
Xiao-Yan Ma;Fu-Qiang Shao;Xinjun Hu;Xingyong Liu
Abstract. N-Acyl-N,O-acetals are key components in a variety of bioactive natural products. Furthermore, they are synthetic equivalents of unstable N-acylimines and building blocks in organic synthesis. Tremendous efforts have been made in the synthesis of such acetals, these methods can be broadly classified into two categories: electrochemical oxidation and chemical methods. Herein, we will summarize progress in the preparation of these subunits, which may aid the development of new synthetic methods for N-acyl-N,O-acetals.1 Introduction2 Synthetic Methods for Preparing N-Acyl-N,O-acetals2.1 Electrochemical Oxidation2.2 Chemical Methods2.3 Other Methods3 Summary and Outlook
