Comparison of the ganglion cell complex and retinal nerve fibre layer measurements using Fourier domain optical coherence tomography to detect ganglion cell loss in non-arteritic anterior ischaemic optic neuropathy
Comparison of the ganglion cell complex and retinal nerve fibre layer measurements using Fourier domain optical coherence tomography to detect ganglion cell loss in non-arteritic anterior ischaemic optic neuropathy
复制标题
DOI：
10.1136/bjophthalmol-2013-303438
复制
发表时间：
2013-08-01
影响因子：
4.1
通讯作者：
Gedik, Sansal
中科院分区：
文献类型：
--
作者：
Gonul, Saban;Koktekir, Bengu Ekinci;Gedik, Sansal
目的探讨黄斑神经节细胞复合体(GCC)和乳头周围神经纤维层(NFL)检测对慢性非动脉炎性前部缺血性视神经病(NAION)患者神经节细胞丢失的诊断价值。测量指标包括：GCC平均厚度、上、下厚度，GCC参数：焦损体积、总体积，神经纤维层厚度：平均、上半球、下半球，视盘参数：边缘面积、边缘体积。绘制受试者特征下面积曲线，评价各参数对GCL的检测能力。
ObjectiveTo evaluate the diagnostic ability of macular ganglion cell complex (GCC) and peripapillary nerve fibre layer (NFL) measurements to detect ganglion cell loss (GCL) in patients with non-arteritic anterior ischaemic optic neuropathy (NAION), at the chronic stage.MethodsThis study included 10 eyes from 10 patients with NAION and 15 eyes from 15 age-matched healthy subjects. The measurements included the GCC thicknesses as average, superior and inferior, the GCC parameters as focal loss volume (FLV) and global loss volume (GLV), the NFL thicknesses as average, superior hemisphere and inferior hemisphere, and the disc parameters as rim area and rim volume. The curves for the area under the receiver operator characteristic (AUROC) were generated to assess the ability of each parameter to detect GCL.ResultsThe patient group had significantly lower GCC thicknesses than the control group (p