Whole Genome Sequence of a Treponema pallidum Strain From a Formalin-Fixed, Paraffin-Embedded Fine Needle Aspirate of a Cervical Lymph Node.
Whole Genome Sequence of a Treponema pallidum Strain From a Formalin-Fixed, Paraffin-Embedded Fine Needle Aspirate of a Cervical Lymph Node.
复制标题
DOI：
10.1097/olq.0000000000001827
复制
发表时间：
2023-08-01
影响因子：
3.1
通讯作者：
中科院分区：
文献类型：
--
作者：
一例怀疑为恶性的单侧颈淋巴肿大患者行细针穿刺。组织学显示混合性炎症浸润伴大量螺旋体。从石蜡包埋的组织切片中提取足够的螺旋体DNA，获得一株大环内酯耐药菌株SS14 ω梅毒螺旋体的近完整基因组序列。
A patient with unilateral cervical lymphadenopathy suspicious for malignancy underwent a fine needle aspiration. Histology demonstrated mixed inflammatory infiltrates with abundant spirochetes. Sufficient spirochete DNA was extracted from paraffin-embedded tissue sections to obtain the near-complete genome sequence of a macrolide resistant strain belonging to the SS14 omega strain of Treponema pallidum.