Estimation of parameters for a model of transmitter release at synapses.
Estimation of parameters for a model of transmitter release at synapses.
复制标题
突触处递质释放模型的参数估计。
作者：
J. Robinson
我们考虑响应神经脉冲释放递质的模型，其中假设递质的量子从 n 个站点中的一些释放，从任何站点释放的概率为 p。假设量子大小是常数或者分布为正态变量或伽玛变量。对自发电位和诱发电位的观察用于获得 n 和 p 的矩估计。给出了这些估计值的标准误差的大样本估计值。
We consider models for the release of transmitter in response to nerve impulses, where it is assumed that quanta of transmitter are released from some of n sites, the probability of release from any site being p. It is assumed that the quantal size is either a constant or is distributed as a normal or a gamma variate. Observations on both spontaneous potentials and evoked potentials are used to obtain moment estimated of n and p. Large sample estimates of the standard errors of these estimates are given.