Vertical transmission of naturally occurring Bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of Lakes Victoria and Baringo in Kenya

Vertical transmission of naturally occurring Bunyamwera and insect-specific flavivirus infections in mosquitoes from islands and mainland shores of Lakes Victoria and Baringo in Kenya
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DOI:
10.1371/journal.pntd.0006949
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发表时间:
2018-11-01
影响因子:
3.8
通讯作者:
Villinger, Jandouwe
Villinger, Jandouwe
中科院分区:
医学2区
文献类型:
--
作者:
Ajamma, Yvonne Ukamaka;Onchuru, Thomas Ogao;Villinger, Jandouwe

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在东非,许多由蚊子传播的虫媒病毒被认为是人类和动物疾病的病原体。虽然近年来虫媒病毒新发传染病的流行频率有所上升,但人们对蚊子在流行间隔期维持病原体循环的程度仍然知之甚少。本研究旨在调查是否虫媒病毒可以保持通过垂直传播,通过不成熟的生命阶段的不同蚊子vector species.MethodologyWe收集的未成熟的蚊子(卵,幼虫,蛹)的海岸和岛屿的巴林戈湖和维多利亚湖在肯尼亚西部和饲养成年人。澳门金沙城中心(
BackgroundMany arboviruses transmitted by mosquitoes have been implicated as causative agents of both human and animal illnesses in East Africa. Although epidemics of arboviral emerging infectious diseases have risen in frequency in recent years, the extent to which mosquitoes maintain pathogens in circulation during inter-epidemic periods is still poorly understood. This study aimed to investigate whether arboviruses may be maintained by vertical transmission via immature life stages of different mosquito vector species.MethodologyWe collected immature mosquitoes (egg, larva, pupa) on the shores and islands of Lake Baringo and Lake Victoria in western Kenya and reared them to adults. Mosquito pools (