Chromogranin A: Is it a useful marker of neuroendocrine tumors?
Chromogranin A: Is it a useful marker of neuroendocrine tumors?
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DOI：
10.1200/jco.2006.10.1535
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发表时间：
2007-05-20
影响因子：
45.3
通讯作者：
Tomassetti, Paola
中科院分区：
文献类型：
--
作者：
Campana, Davide;Nori, Francesca;Tomassetti, Paola
我们评估了大量神经内分泌肿瘤（NETS）患者、一系列伴有或不伴有肠嗜铬样（ECL）细胞增生的慢性萎缩性胃炎（CAG）患者以及健康参与者（HPs）中嗜铬粒蛋白A（CgA）血浆水平的模式。48个HP。结果NETS患者血浆CgA水平明显高于CAG患者和HP患者（P
PurposeWe evaluated the pattern of chromogranin A (CgA) plasma levels in a large number of patients with neuroendocrine tumors (NETS), in a series of patients with chronic atrophic gastritis (CAG) with and without enterochromaffin-like (ECL) cell hyperplasia, and in healthy participants (HPs).Patients and MethodsTwo hundred thirty-eight patients with NETS, 42 patients with CAG with or without ECL cell hyperplasia, and 48 HPs were studied. All patients underwent a baseline visit, biochemical routine check-up, imaging techniques, endoscopy, and histologic determination.ResultsCgA plasma levels were higher in patients with NETS compared with CAG patients or HPs (P